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Characterising molecules

Synthesis of paracetamol

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In this resource, students explore the synthesis of paracetamol, initially by carrying out a risk assessment, then interpreting experimental results by calculating yield, analysing a TLC plate, IR spectra and CNMR spectra.

Learning outcomes

  • Determine the hazards and risks involved in the experiment.
  • Calculate the yield of the synthesis.
  • Interpret TLC and melting point data to determine the purity of the synthesised product.
  • Interpret spectra relating to the synthesis.
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Skills

Working in a Safe Manner

  • How to identify experimental hazards and proper disposal methods.

Manipulating and Presenting Data

  • How to calculate the yield and Rf values.

Concepts, Principles and Theories

  • How to interpret TLC and melting point data to determine the purity of the synthesised product.
  • How to interpret spectra relating to the synthesis.

Learn more about our approach to skills
Prof. Dudley Shallcross
Professor of Atmospheric Chemistry, University of Bristol

“Smart Worksheets give educators a vast quantity of data on what their students can do and what they are struggling with. This allows academics to tailor workshops and other feedback opportunities to support cognition.”

Details

Degrees

Chemistry
Biochemistry

Modules

Biological chemistry
Preparative chemistry
Purification
Quantitative chemistry

Topic

Characterising molecules

Purchase option

The Smart Worksheet Library

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